Practical Method for Preparation of (S)-2-Amino-5,5,5-trifluoropentanoic Acid via Dynamic Kinetic Resolution

[Image: see text] This work reports an operationally convenient ∼20 g scale synthesis of (S)-2-amino-5,5,5-trifluoropentanoic acid and its Fmoc-derivative via dynamic kinetic resolution of the corresponding racemate.

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Mei, Haibo, Han, Jianlin, Takeda, Ryosuke, Sakamoto, Tsubasa, Miwa, Toshio, Minamitsuji, Yutaka, Moriwaki, Hiroki, Abe, Hidenori, Soloshonok, Vadim A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682081/
https://ncbi.nlm.nih.gov/pubmed/31460294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01537
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