Tumour infiltrating lymphocytes and immune-related genes as predictors of outcome in pancreatic adenocarcinoma

BACKGROUND: We investigated the correlation between pancreatic ductal adenocarcinoma patient prognosis and the presence of tumour infiltrating lymphocytes and expression of 521 immune system genes. METHODS: Intratumoural CD3+, CD8+, and CD20+ lymphocytes were examined by immunohistochemistry in 12 P...

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Udgivet i:PLoS One
Main Authors: D’Angelo, Alberto, Sobhani, Navid, Roviello, Giandomenico, Bagby, Stefan, Bonazza, Deborah, Bottin, Cristina, Giudici, Fabiola, Zanconati, Fabrizio, De Manzini, Nicolo, Guglielmi, Alessandra, Generali, Daniele
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681957/
https://ncbi.nlm.nih.gov/pubmed/31381571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219566
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