Cyclin dependent kinase 4 and 6 inhibitors as novel therapeutic agents for targeted treatment of malignant mesothelioma

Malignant Mesothelioma (MM) is a rare and aggressive form of tumour that affects the lining of the internal organs for which current treatments have not been proven to be very effective. P16(INK4A) tumour suppressor encoding CDKN2A gene is often downregulated in MM. This protein is a cyclin dependen...

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Bibliographic Details
Published in:Genes Cancer
Main Authors: Sobhani, Navid, Corona, Silvia P., Zanconati, Fabrizio, Generali, Daniele
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
Subjects:
Research Perspective
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489646/
https://ncbi.nlm.nih.gov/pubmed/28680533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.138
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