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Subchronic Toxicity of Silica Nanoparticles as a Function of Size and Porosity

Despite increasing reports of using silica nanoparticles (SNPs) for controlled drug delivery applications, their long-term toxicity profile following intravenous administration remains unexplored. Herein, we investigated the acute (10-day) and subchronic (60-day and 180-day) toxicity of nonporous SN...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Mohammadpour, Raziye, Yazdimamaghani, Mostafa, Cheney, Darwin L., Jedrzkiewicz, Jolanta, Ghandehari, Hamidreza
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681828/
https://ncbi.nlm.nih.gov/pubmed/31047961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.04.041
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