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One-year Chronic Toxicity Evaluation of Single Dose Intravenously Administered Silica Nanoparticles in Mice and their Ex vivo Human Hemocompatibility

Chronic toxicity evaluations of nanotechnology-based drugs are essential to support initiation of clinical trials. Ideally such evaluations should address the dosing strategy in human applications and provide sufficient information for long-term usage. Herein, we investigated one-year toxicity of no...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Mohammadpour, Raziye, Cheney, Darwin L., Grunberger, Jason W., Yazdimamaghani, Mostafa, Jedrzkiewicz, Jolanta, Isaacson, Kyle J., Dobrovolskaia, Marina A., Ghandehari, Hamidreza
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429347/
https://ncbi.nlm.nih.gov/pubmed/32464151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.05.027
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