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Impact of antibiotic treatment and host innate immune pressure on enterococcal adaptation in the human bloodstream

Multidrug-resistant enterococcal strains emerged in the early 1980s and are now among the leading causes of drug-resistant bacterial infection worldwide. We used functional genomics to study an early bacterial outbreak in patients in a Wisconsin hospital between 1984 and 1988 that was caused by mult...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Transl Med
Hauptverfasser: Tyne, Daria Van, Manson, Abigail L., Huycke, Mark M., Karanicolas, John, Earl, Ashlee M., Gilmore, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681809/
https://ncbi.nlm.nih.gov/pubmed/30971455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat8418
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