Melanocortin 1 Receptor–Targeted α-Particle Therapy for Metastatic Uveal Melanoma

New effective therapies are greatly needed for metastatic uveal melanoma, which has a very poor prognosis with a median survival of less than 1 y. The melanocortin 1 receptor (MC1R) is expressed in 94% of uveal melanoma metastases, and a MC1R-specific ligand (MC1RL) with high affinity and selectivit...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Tafreshi, Narges K., Tichacek, Christopher J., Pandya, Darpan N., Doligalski, Michael L., Budzevich, Mikalai M., Kil, HyunJoo, Bhatt, Nikunj B., Kock, Nancy D., Messina, Jane L., Ruiz, Epifanio E., Delva, Nella C., Weaver, Adam, Gibbons, William R., Boulware, David C., Khushalani, Nikhil I., El-Haddad, Ghassan, Triozzi, Pierre L., Moros, Eduardo G., McLaughlin, Mark L., Wadas, Thaddeus J., Morse, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2019
Assuntos:
Theranostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681690/
https://ncbi.nlm.nih.gov/pubmed/30733316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.217240
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