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Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes
The mitotic spindle is a microtubule-based machine that segregates a replicated set of chromosomes during cell division. Many cancer drugs alter or disrupt the microtubules that form the mitotic spindle. Microtubule-dependent molecular motors that function during mitosis are logical alternative mito...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6681659/ https://ncbi.nlm.nih.gov/pubmed/30528696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.12.008 |
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