Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer

BACKGROUND: Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive and lethal disease, lacking effective therapeutic approaches. Available therapies only marginally prolong patient survival and are frequently coupled with severe adverse events. It is therefore pivotal to investigate novel and safe...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Adamska, Aleksandra, Domenichini, Alice, Capone, Emily, Damiani, Verena, Akkaya, Begum Gokcen, Linton, Kenneth J., Di Sebastiano, Pierluigi, Chen, Xi, Keeton, Adam B., Ramirez-Alcantara, Veronica, Maxuitenko, Yulia, Piazza, Gary A., De Laurenzi, Vincenzo, Sala, Gianluca, Falasca, Marco
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681491/
https://ncbi.nlm.nih.gov/pubmed/31378204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1308-7
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