The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance

Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major negative regulator for insulin receptor signaling and a novel molecular player in e...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Abdelsalam, Shahenda S., Korashy, Hesham M., Zeidan, Asad, Agouni, Abdelali
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680919/
https://ncbi.nlm.nih.gov/pubmed/31319588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9070286
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