Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction

Upon increased demand for protein synthesis, accumulation of misfolded and/or unfolded proteins within the endoplasmic reticulum (ER), a pro-survival response is activated termed unfolded protein response (UPR), aiming at restoring the proper function of the ER. Prolonged activation of the UPR leads...

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Detalhes bibliográficos
Main Authors: Aisha Osman, Tarek Benameur, Hesham M. Korashy, Asad Zeidan, Abdelali Agouni
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-10-01
Colecção:Biomedicines
Assuntos:
extracellular vesicles (EVs)
microparticles (MPs)
endoplasmic reticulum (ER) stress
endothelial dysfunction
cardiovascular disease
diabetes
Acesso em linha:https://www.mdpi.com/2227-9059/8/10/409
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