Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled In Silico-Experimental Studies. Part I: Covalent siRNA Nanocarriers

Small interfering RNAs (siRNAs) represent a new approach towards the inhibition of gene expression; as such, they have rapidly emerged as promising therapeutics for a plethora of important human pathologies including cancer, cardiovascular diseases, and other disorders of a genetic etiology. However...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharmaceutics
Main Authors: Marson, Domenico, Laurini, Erik, Aulic, Suzana, Fermeglia, Maurizio, Pricl, Sabrina
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680565/
https://ncbi.nlm.nih.gov/pubmed/31323863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11070351
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