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High Impact: The Role of Promiscuous Binding Sites in Polypharmacology

The literature focuses on drug promiscuity, which is a drug’s ability to bind to several targets, because it plays an essential role in polypharmacology. However, little work has been completed regarding binding site promiscuity, even though its properties are now recognized among the key factors th...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Cerisier, Natacha, Petitjean, Michel, Regad, Leslie, Bayard, Quentin, Réau, Manon, Badel, Anne, Camproux, Anne-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680532/
https://ncbi.nlm.nih.gov/pubmed/31295958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24142529
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