Betulin Promotes Differentiation of Human Osteoblasts In Vitro and Exerts an Osteoinductive Effect on the hFOB 1.19 Cell Line Through Activation of JNK, ERK1/2, and mTOR Kinases

Although betulin (BET), a naturally occurring pentacyclic triterpene, has a variety of biological activities, its osteogenic potential has not been investigated so far. The aim of this study was to assess the effect of BET on differentiation of human osteoblasts (hFOB 1.19 and Saos-2 cells) in vitro...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Mizerska-Kowalska, Magdalena, Sławińska-Brych, Adrianna, Kaławaj, Katarzyna, Żurek, Aleksandra, Pawińska, Beata, Rzeski, Wojciech, Zdzisińska, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680433/
https://ncbi.nlm.nih.gov/pubmed/31331121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24142637
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