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Multilayer-Coated Tablet of Clopidogrel and Rosuvastatin: Preparation and In Vitro/In vivo Characterization

The acid lability of rosuvastatin hinders the preparation of mixed combination formulations of rosuvastatin with acidic drugs such as clopidogrel. Therefore, the purpose of this study was to develop a multilayer-coated tablet that avoids physicochemical interactions between rosuvastatin and clopidog...

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Publicat a:Pharmaceutics
Autors principals: Seo, Ki-Soo, Han, Hyo-Kyung
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680394/
https://ncbi.nlm.nih.gov/pubmed/31277408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11070313
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