Development of an M cell targeted nanocomposite system for effective oral protein delivery: preparation, in vitro and in vivo characterization

BACKGROUND: There is a strong need for non-invasive and patient-friendly delivery systems of protein drugs for long-term therapy. However, oral delivery of protein drugs is a big challenge due to many barriers including instability in the gastrointestinal (GI) tract and low permeability. To overcome...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Nanobiotechnology
Main Authors: Song, Jae Geun, Lee, Sang Hoon, Han, Hyo-Kyung
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796596/
https://ncbi.nlm.nih.gov/pubmed/33422063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00750-y
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