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An Expedient Total Synthesis of Chivosazole F: an Actin‐Binding Antimitotic Macrolide from the Myxobacterium Sorangium Cellulosum
A unified strategy for the chemical synthesis of the chivosazoles is described. This strategy is based on two closely related approaches involving the late‐stage installation of the isomerization‐prone (2Z,4E,6Z,8E)‐tetraenoate motif, and an expedient fragment‐assembly procedure. The result is a hig...
Gorde:
| Argitaratua izan da: | Angew Chem Int Ed Engl |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6680201/ https://ncbi.nlm.nih.gov/pubmed/27897365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201610636 |
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