Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue

Insulin orchestrates metabolic homeostasis through a complex signaling network for which the precise mechanisms controlling its fine‐tuning are not completely understood. Here, we report that Afadin, a scaffold protein, is phosphorylated on S1795 (S1718 in humans) in response to insulin in adipocyte...

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Bibliografiska uppgifter
I publikationen:EMBO Rep
Huvudupphovsmän: Lundh, Morten, Petersen, Patricia SS, Isidor, Marie S, Kazoka‐Sørensen, Dolly NM, Plucińska, Kaja, Shamsi, Farnaz, Ørskov, Cathrine, Tozzi, Marco, Brown, Erin L, Andersen, Emil, Ma, Tao, Müller, Ulrich, Barrès, Romain, Kristiansen, Viggo B, Gerhart‐Hines, Zachary, Tseng, Yu‐Hua, Emanuelli, Brice
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680131/
https://ncbi.nlm.nih.gov/pubmed/31264358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948216
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