Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue

Insulin orchestrates metabolic homeostasis through a complex signaling network for which the precise mechanisms controlling its fine‐tuning are not completely understood. Here, we report that Afadin, a scaffold protein, is phosphorylated on S1795 (S1718 in humans) in response to insulin in adipocyte...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Lundh, Morten, Petersen, Patricia SS, Isidor, Marie S, Kazoka‐Sørensen, Dolly NM, Plucińska, Kaja, Shamsi, Farnaz, Ørskov, Cathrine, Tozzi, Marco, Brown, Erin L, Andersen, Emil, Ma, Tao, Müller, Ulrich, Barrès, Romain, Kristiansen, Viggo B, Gerhart‐Hines, Zachary, Tseng, Yu‐Hua, Emanuelli, Brice
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680131/
https://ncbi.nlm.nih.gov/pubmed/31264358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948216
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