Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue

Insulin orchestrates metabolic homeostasis through a complex signaling network for which the precise mechanisms controlling its fine‐tuning are not completely understood. Here, we report that Afadin, a scaffold protein, is phosphorylated on S1795 (S1718 in humans) in response to insulin in adipocyte...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Lundh, Morten, Petersen, Patricia SS, Isidor, Marie S, Kazoka‐Sørensen, Dolly NM, Plucińska, Kaja, Shamsi, Farnaz, Ørskov, Cathrine, Tozzi, Marco, Brown, Erin L, Andersen, Emil, Ma, Tao, Müller, Ulrich, Barrès, Romain, Kristiansen, Viggo B, Gerhart‐Hines, Zachary, Tseng, Yu‐Hua, Emanuelli, Brice
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680131/
https://ncbi.nlm.nih.gov/pubmed/31264358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948216
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