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Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
OBJECTIVE: Functional investigation of novel gene/protein targets associated with adipocyte differentiation or function heavily relies on efficient and accessible tools to manipulate gene expression in adipocytes in vitro. Recent advances in gene-editing technologies such as CRISPR-Cas9 have not onl...
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| Udgivet i: | Mol Metab |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5641601/ https://ncbi.nlm.nih.gov/pubmed/29031730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.07.001 |
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