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Persistence of Integrase-Deficient Lentiviral Vectors correlates with the induction of STING-independent CD8(+) T cell responses
Lentiviruses are among the most promising viral vectors for in vivo gene delivery. To overcome the risk of insertional mutagenesis, integrase-deficient lentiviral vectors (IDLVs) have been developed. We show here that strong and persistent specific cytotoxic T cell (CTL) responses are induced by IDL...
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| Published in: | Cell Rep |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6679900/ https://ncbi.nlm.nih.gov/pubmed/30699352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.025 |
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