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Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca(2+) signaling
Acidic organelles, such as endosomes and lysosomes, store Ca(2+) that is released in response to intracellular increases in the second messenger nicotinic acid adenine dinucleotide phosphate (NAADP). In neurons, NAADP and Ca(2+) signaling contribute to synaptic plasticity, a process of activity-depe...
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| 發表在: | Sci Signal |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6679716/ https://ncbi.nlm.nih.gov/pubmed/30482851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aat9093 |
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