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Controlling, understanding, and redirecting the thermal rearrangement of 3,3-dicyano-1,5-enynes

The thermal [3,3] rearrangement of 3,3-di-cyano-1,5-enynes to γ-allenyl alkylidenemalononitriles (the “enyne Cope rearrangement”) has largely eluded synthetic value as the desired products, too, are thermally reactive and ultimately yield 6π electrocyclization products. Herein, we describe experimen...

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Publicat a:J Am Chem Soc
Autors principals: Scott, Sarah K., Sanders, Jacob N., White, Katherine E., Yu, Roland A., Houk, K. N., Grenning, Alexander J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679653/
https://ncbi.nlm.nih.gov/pubmed/30379070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08553
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