Brexpiprazole, a Serotonin-Dopamine Activity Modulator, Can Sensitize Glioma Stem Cells to Osimertinib, a Third-Generation EGFR-TKI, via Survivin Reduction

Glioblastoma is a primary brain tumor associated with a poor prognosis due to its high chemoresistance capacity. Cancer stem cells (CSCs) are one of the mechanisms of chemoresistance. Although therapy targeting CSCs is promising, strategies targeting CSCs remain unsuccessful. Abnormal activation of...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Suzuki, Shuhei, Yamamoto, Masahiro, Sanomachi, Tomomi, Togashi, Keita, Sugai, Asuka, Seino, Shizuka, Yoshioka, Takashi, Kitanaka, Chifumi, Okada, Masashi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679129/
https://ncbi.nlm.nih.gov/pubmed/31284441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11070947
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