Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disorder. It is mainly caused by mutations in genes encoding sarcomere proteins. Mutant forms of these highly abundant proteins likely stress the protein quality control (PQC) system of cardiomyocytes. The PQC system, together wi...

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Vydáno v:Cells
Hlavní autoři: Dorsch, Larissa M., Schuldt, Maike, dos Remedios, Cristobal G., Schinkel, Arend F. L., de Jong, Peter L., Michels, Michelle, Kuster, Diederik W. D., Brundel, Bianca J. J. M., van der Velden, Jolanda
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678711/
https://ncbi.nlm.nih.gov/pubmed/31323898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8070741
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