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Primary Human Fibroblasts in Culture Switch to a Myofibroblast-Like Phenotype Independently of TGF Beta

Fibroblasts are the prevalent cell type and main source for extracellular matrix (ECM) in connective tissue. Depending on their origin, fibroblasts play a central role in non-pathological tissue remodeling and disease like fibrosis. This study examined the effect of established culture conditions of...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Baranyi, Ulrike, Winter, Birgitta, Gugerell, Alfred, Hegedus, Balazs, Brostjan, Christine, Laufer, Günther, Messner, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678602/
https://ncbi.nlm.nih.gov/pubmed/31337073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8070721
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