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In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice

Osteosarcoma, the most common bone malignancy with a peak incidence at adolescence, had no survival improvement since decades. Persistent problems are chemo-resistance and metastatic spread. We developed in-vitro osteosarcoma models resistant to chemotherapy and in-vivo bioluminescent orthotopic cel...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Marques da Costa, Maria Eugénia, Marchais, Antonin, Gomez-Brouchet, Anne, Job, Bastien, Assoun, Noémie, Daudigeos-Dubus, Estelle, Fromigué, Olivia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678535/
https://ncbi.nlm.nih.gov/pubmed/31319571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11070997
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