Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

Here, we discovered an endogenous dafachronic acid (DA) in the socioeconomically important parasitic nematode Haemonchus contortus. We demonstrate that DA promotes larval exsheathment and development in this nematode via a relatively conserved nuclear hormone receptor (DAF-12). This stimulatory effe...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS Pathog
Hlavní autoři: Ma, Guangxu, Wang, Tao, Korhonen, Pasi K., Young, Neil D., Nie, Shuai, Ang, Ching-Seng, Williamson, Nicholas A., Reid, Gavin E., Gasser, Robin B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677322/
https://ncbi.nlm.nih.gov/pubmed/31335899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007960
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky