Tanshinone IIA Exerts Anti-Inflammatory and Immune-Regulating Effects on Vulnerable Atherosclerotic Plaque Partially via the TLR4/MyD88/NF-κB Signal Pathway

Background: Tanshinone IIA (Tan IIA), a lipophilic constituent from Salvia miltiorrhiza Bunge, has shown a promising cardioprotective effect including anti-atherosclerosis. This study aims at exploring Tan IIA’s anti-inflammatory and immune-regulating roles in stabilizing vulnerable atherosclerotic...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Chen, Zhuo, Gao, Xiang, Jiao, Yang, Qiu, Yu, Wang, Anlu, Yu, Meili, Che, Fangyuan, Li, Siming, Liu, Jing, Li, Jingen, Zhang, He, Yu, Changan, Li, Geng, Gao, Yanxiang, Pan, Lin, Sun, Weiliang, Guo, Jing, Cao, Bingyan, Zhu, Yilin, Xu, Hao
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677033/
https://ncbi.nlm.nih.gov/pubmed/31402870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00850
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