Total tanshinones exhibits anti-inflammatory effects through blocking TLR4 dimerization via the MyD88 pathway

Tanshinones belong to a group of lipophilic constituents of Salvia miltiorrhiza Bunge (Danshen), which is widely used in traditional Chinese medicine. A deluge of studies demonstrated that tanshinones exert anti-inflammatory effects, but the underlying mechanisms remain unclear to date. This study i...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gao, Hongwei, Liu, Xin, Sun, Wen, Kang, Naixin, Liu, Yanli, Yang, Shilin, Xu, Qiong-ming, Wang, Chunming, Chen, Xiuping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596575/
https://ncbi.nlm.nih.gov/pubmed/28817116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.389
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