Assignment of virus and antimicrobial resistance genes to microbial hosts in a complex microbial community by combined long-read assembly and proximity ligation

We describe a method that adds long-read sequencing to a mix of technologies used to assemble a highly complex cattle rumen microbial community, and provide a comparison to short read-based methods. Long-read alignments and Hi-C linkage between contigs support the identification of 188 novel virus-h...

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Publicat a:Genome Biol
Autors principals: Bickhart, Derek M., Watson, Mick, Koren, Sergey, Panke-Buisse, Kevin, Cersosimo, Laura M., Press, Maximilian O., Van Tassell, Curtis P., Van Kessel, Jo Ann S., Haley, Bradd J., Kim, Seon Woo, Heiner, Cheryl, Suen, Garret, Bakshy, Kiranmayee, Liachko, Ivan, Sullivan, Shawn T., Myer, Phillip R., Ghurye, Jay, Pop, Mihai, Weimer, Paul J., Phillippy, Adam M., Smith, Timothy P. L.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676630/
https://ncbi.nlm.nih.gov/pubmed/31375138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1760-x
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