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Scaffolding of long read assemblies using long range contact information

BACKGROUND: Long read technologies have revolutionized de novo genome assembly by generating contigs orders of magnitude longer than that of short read assemblies. Although assembly contiguity has increased, it usually does not reconstruct a full chromosome or an arm of the chromosome, resulting in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Ghurye, Jay, Pop, Mihai, Koren, Sergey, Bickhart, Derek, Chin, Chen-Shan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508778/
https://ncbi.nlm.nih.gov/pubmed/28701198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3879-z
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