Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

BACKGROUND: Patients with rheumatoid arthritis (RA) experience extra-articular manifestations including osteoporosis and muscle wasting, which closely associate with severity of disease. Whilst therapeutic glucocorticoids (GCs) reduce inflammation in RA, their actions on muscle and bone metabolism i...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Fenton, C. G., Webster, J. M., Martin, C. S., Fareed, S., Wehmeyer, C., Mackie, H., Jones, R., Seabright, A. P., Lewis, J. W., Lai, Y. C., Goodyear, C. S., Jones, S. W, Cooper, M. S., Lavery, G. G., Langen, R., Raza, K., Hardy, R. S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676537/
https://ncbi.nlm.nih.gov/pubmed/31370858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1962-3
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