The effects of increased acetate turnover on glucose-induced insulin secretion in lean and obese humans

INTRODUCTION: Increased endogenous acetate production (Ra) in rodents has been shown to activate the parasympathetic nervous system and thereby promote increased glucose-stimulated insulin secretion (GSIS), increased ghrelin secretion, hyperphagia and obesity. AIM: To examine whether rates of acetat...

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Bibliographic Details
Published in:J Clin Transl Sci
Main Authors: Petersen, Kitt Falk, Impellizeri, Anne, Cline, Gary W., Shulman, Gerald I.
Format: Artigo
Language:Inglês
Published: Cambridge University Press 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676497/
https://ncbi.nlm.nih.gov/pubmed/31404159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.342
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