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Antagonism of the Kappa Opioid Receptor Attenuates THC-Induced Place Aversions in Adult Male Sprague-Dawley Rats

RATIONALE: Prior research with transgenic mice in which the kappa opioid receptor (KOR) has been suppressed or activated suggests that the aversive effects of THC are mediated by activity of this receptor subtype. If the activity of the KOR system is responsible for mediating the THC’s aversive effe...

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Vydáno v:Pharmacol Biochem Behav
Hlavní autoři: Clasen, Matthew M., Flax, Shaun M., Hempel, Briana J., Cheng, Kejun, Rice, Kenner C., Riley, Anthony L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676491/
https://ncbi.nlm.nih.gov/pubmed/29100992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2017.10.010
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