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Antagonism of the Kappa Opioid Receptor Attenuates THC-Induced Place Aversions in Adult Male Sprague-Dawley Rats

RATIONALE: Prior research with transgenic mice in which the kappa opioid receptor (KOR) has been suppressed or activated suggests that the aversive effects of THC are mediated by activity of this receptor subtype. If the activity of the KOR system is responsible for mediating the THC’s aversive effe...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Clasen, Matthew M., Flax, Shaun M., Hempel, Briana J., Cheng, Kejun, Rice, Kenner C., Riley, Anthony L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676491/
https://ncbi.nlm.nih.gov/pubmed/29100992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2017.10.010
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