Exosomal microRNAs derived from colon cancer cells promote tumor progression by suppressing fibroblast TP53 expression

The tumor microenvironment offers favorable conditions for tumor progression, and activated fibroblasts, known as cancer‐associated fibroblasts, play a pivotal role. TP53‐deficient cancer cells are known to induce strong fibroblast activation. We aimed to elucidate the oncogenic role of exosomes der...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Sci
Egile Nagusiak: Yoshii, Shunsuke, Hayashi, Yoshito, Iijima, Hideki, Inoue, Takanori, Kimura, Keiichi, Sakatani, Akihiko, Nagai, Kengo, Fujinaga, Tetsuji, Hiyama, Satoshi, Kodama, Takahiro, Shinzaki, Shinichiro, Tsujii, Yoshiki, Watabe, Kenji, Takehara, Tetsuo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676271/
https://ncbi.nlm.nih.gov/pubmed/31148360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14084
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