Exosomal microRNAs derived from colon cancer cells promote tumor progression by suppressing fibroblast TP53 expression

The tumor microenvironment offers favorable conditions for tumor progression, and activated fibroblasts, known as cancer‐associated fibroblasts, play a pivotal role. TP53‐deficient cancer cells are known to induce strong fibroblast activation. We aimed to elucidate the oncogenic role of exosomes der...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Yoshii, Shunsuke, Hayashi, Yoshito, Iijima, Hideki, Inoue, Takanori, Kimura, Keiichi, Sakatani, Akihiko, Nagai, Kengo, Fujinaga, Tetsuji, Hiyama, Satoshi, Kodama, Takahiro, Shinzaki, Shinichiro, Tsujii, Yoshiki, Watabe, Kenji, Takehara, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676271/
https://ncbi.nlm.nih.gov/pubmed/31148360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14084
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