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Increases in Soluble Protein Oligomers Trigger the Innate Immune System Promoting Inflammation and Vascular Dysfunction in the Pathogenesis of Sepsis

Sepsis is a profoundly morbid and life-threatening condition, and an increasingly alarming burden on modern healthcare economies. Patients with septic shock exhibit persistent hypotension despite adequate volume resuscitation requiring pharmacological vasoconstrictors, but the molecular mechanisms o...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Sci (Lond)
Hauptverfasser: Komic, Amel, Martinez-Quinones, Patricia, McCarthy, Cameron G, Webb, R. Clinton, Wenceslau, Camilla F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676213/
https://ncbi.nlm.nih.gov/pubmed/30021912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20180368
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