Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity

The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally painful orthopaedic hand surgery (trapeziectomy). Further investigations revealed...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Anaesth
Prif Awduron: Habib, Abdella M., Okorokov, Andrei L., Hill, Matthew N., Bras, Jose T., Lee, Man-Cheung, Li, Shengnan, Gossage, Samuel J., van Drimmelen, Marie, Morena, Maria, Houlden, Henry, Ramirez, Juan D., Bennett, David L.H., Srivastava, Devjit, Cox, James J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019
Pynciau:
Pain Mechanisms and Novel Analgesic
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676009/
https://ncbi.nlm.nih.gov/pubmed/30929760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2019.02.019
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