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Zika Virus Production Is Resistant to RNase L Antiviral Activity

There is currently no knowledge of how the emerging human pathogen Zika virus (ZIKV) interacts with the antiviral endoribonuclease L (RNase L) pathway during infection. Since activation of RNase L during infection typically limits virus production dramatically, we used CRISPR-Cas9 gene editing techn...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Whelan, Jillian N., Li, Yize, Silverman, Robert H., Weiss, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675901/
https://ncbi.nlm.nih.gov/pubmed/31142667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00313-19
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