Quantifying Between-Cohort and Between-Sex Genetic Heterogeneity in Major Depressive Disorder

Major depressive disorder (MDD) is clinically heterogeneous with prevalence rates twice as high in women as in men. There are many possible sources of heterogeneity in MDD most of which are not measured in a sufficiently comparable way across study samples. Here, we assess genetic heterogeneity base...

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Udgivet i:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Trzaskowski, Maciej, Mehta, Divya, Peyrot, Wouter, Hawkes, David, Davies, Daniel, Howard, David, Kemper, Kathryn E., Sidorenko, Julia, Maier, Robert, Ripke, Stephan, Mattheisen, Manuel, Baune, Bernhard T, Grabe, Hans J., Heath, Andrew C, Jones, Lisa, Jones, Ian, Madden, Pamela AF, McIntosh, Andrew M., Breen, Gerome, Lewis, Cathryn M., Børglum, Anders D., Sullivan, Patrick F., Martin, Nicholas G., Kendler, Kenneth S., Levinson, Douglas F., Wray, Naomi R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675638/
https://ncbi.nlm.nih.gov/pubmed/30708398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32713
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