Cardiorespiratory fitness modifies influence of sleep problems on CSF biomarkers in an at-risk cohort

BACKGROUND: Previous studies indicate that cardiorespiratory fitness (CRF) and sleep are each favorably associated with Alzheimer’s disease (AD) pathophysiology, including reduced amyloid-beta (Aβ) and tau pathology. However, few studies have examined CRF and sleep in the same analysis. OBJECTIVE: T...

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Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Law, Lena L., Sprecher, Kate E., Dougherty, Ryan J., Edwards, Dorothy F., Koscik, Rebecca L., Gallagher, Catherine L., Carlsson, Cynthia M., Zetterberg, Henrik, Blennow, Kaj, Asthana, Sanjay, Sager, Mark A., Hermann, Bruce P., Johnson, Sterling C., Cook, Dane B., Bendlin, Barbara B., Okonkwo, Ozioma C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675618/
https://ncbi.nlm.nih.gov/pubmed/30958346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180291
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