Cardiorespiratory fitness modifies influence of sleep problems on CSF biomarkers in an at-risk cohort

BACKGROUND: Previous studies indicate that cardiorespiratory fitness (CRF) and sleep are each favorably associated with Alzheimer’s disease (AD) pathophysiology, including reduced amyloid-beta (Aβ) and tau pathology. However, few studies have examined CRF and sleep in the same analysis. OBJECTIVE: T...

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Vydáno v:J Alzheimers Dis
Hlavní autoři: Law, Lena L., Sprecher, Kate E., Dougherty, Ryan J., Edwards, Dorothy F., Koscik, Rebecca L., Gallagher, Catherine L., Carlsson, Cynthia M., Zetterberg, Henrik, Blennow, Kaj, Asthana, Sanjay, Sager, Mark A., Hermann, Bruce P., Johnson, Sterling C., Cook, Dane B., Bendlin, Barbara B., Okonkwo, Ozioma C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675618/
https://ncbi.nlm.nih.gov/pubmed/30958346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180291
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