Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder

Mitochondrial dysfunction characterizes many rare and common age-associated diseases. The biochemical consequences, underlying clinical manifestations, and potential therapeutic targets, remain to be better understood. We tested the hypothesis that lipid dyshomeostasis in mitochondrial disorders goe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ruiz, Matthieu, Cuillerier, Alexanne, Daneault, Caroline, Deschênes, Sonia, Frayne, Isabelle Robillard, Bouchard, Bertrand, Forest, Anik, Legault, Julie Thompson, Vaz, Frederic M., Rioux, John D., Burelle, Yan, Des Rosiers, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675547/
https://ncbi.nlm.nih.gov/pubmed/31341105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123231
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados