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Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors during Obesity-Induced Adipose Tissue Fibrosis

Adipose tissue fibrosis is associated with inflammation and insulin resistance in human obesity. In particular, visceral fat fibrosis is correlated with hyperlipidemia and ectopic fat accumulation. Myocardin-related transcription factor A (MRTFA) is an important coactivator that mediates the transcr...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: Lin, Jean Z., Rabhi, Nabil, Farmer, Stephen R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675460/
https://ncbi.nlm.nih.gov/pubmed/29768198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.057
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