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Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors during Obesity-Induced Adipose Tissue Fibrosis

Adipose tissue fibrosis is associated with inflammation and insulin resistance in human obesity. In particular, visceral fat fibrosis is correlated with hyperlipidemia and ectopic fat accumulation. Myocardin-related transcription factor A (MRTFA) is an important coactivator that mediates the transcr...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Lin, Jean Z., Rabhi, Nabil, Farmer, Stephen R.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675460/
https://ncbi.nlm.nih.gov/pubmed/29768198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.057
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