Essential Contribution of the Ligand-Binding βB/βC Loop of PDZ1 and PDZ2 in the Regulation of Postsynaptic Clustering, Scaffolding, and Localization of Postsynaptic Density-95

Postsynaptic density-95 (PSD-95), a PSD-95/Discs large/zona occludens-1 (PDZ) domain-containing scaffold protein, clusters many signaling molecules near NMDA-type glutamate receptors in the postsynaptic densities. Although the synaptic localization of PSD-95 requires palmitoylation of two cysteines...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Nonaka, Mio, Doi, Tomoko, Fujiyoshi, Yoshinori, Takemoto-Kimura, Sayaka, Bito, Haruhiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2006
Materias:
Cellular/Molecular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675374/
https://ncbi.nlm.nih.gov/pubmed/16421296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2489-05.2006
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