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A Nitrone Dipolar Cycloaddition Strategy toward an Enantioselective Synthesis of Massadine

An enantioselective route to the C,D-bicycle of massadine is reported. Enantiopure intermediates were generated by a single stereoselective reduction using the Corey–Bakshi–Shibata reagent. This initial stereoinduction was translated into the five contiguous stereocenters of the massadine D-ring by...

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Bibliographic Details
Published in:Org Lett
Main Author: Cannon, Jeffrey S.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674976/
https://ncbi.nlm.nih.gov/pubmed/29897770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01464
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