Na(v)1.7 Mutant A863P in Erythromelalgia: Effects of Altered Activation and Steady-State Inactivation on Excitability of Nociceptive Dorsal Root Ganglion Neurons

Inherited erythromelalgia/erythermalgia (IEM) is a neuropathy characterized by pain and redness of the extremities that is triggered by warmth. IEM has been associated with missense mutations of the voltage-gated sodium channel Na(v)1.7, which is preferentially expressed in most nociceptive dorsal r...

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Publicado no:J Neurosci
Main Authors: Harty, T. Patrick, Dib-Hajj, Sulayman D., Tyrrell, Lynda, Blackman, Rachael, Hisama, Fuki M., Rose, John B., Waxman, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674913/
https://ncbi.nlm.nih.gov/pubmed/17135418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3424-06.2006
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