A Gain-of-Function Mutation in Synaptotagmin-1 Reveals a Critical Role of Ca(2+)-Dependent Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Complex Binding in Synaptic Exocytosis

Synaptotagmin-1, the Ca(2+) sensor for fast neurotransmitter release, was proposed to function by Ca(2+)-dependent phospholipid binding and/or by Ca(2+)-dependent soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex binding. Extensive in vivo data support the first h...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Pang, Zhiping P., Shin, Ok-Ho, Meyer, Alexander C., Rosenmund, Christian, Südhof, Thomas C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2006
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674888/
https://ncbi.nlm.nih.gov/pubmed/17135417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3804-06.2006
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