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Alternative Splicing of the Ca(V)1.3 Channel IQ Domain, a Molecular Switch for Ca(2+)-Dependent Inactivation within Auditory Hair Cells

Native Ca(V)1.3 channels within cochlear hair cells exhibit a surprising lack of Ca(2+)-dependent inactivation (CDI), given that heterologously expressed Ca(V)1.3 channels show marked CDI. To determine whether alternative splicing at the C terminus of the Ca(V)1.3 gene may produce a hair cell splice...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Shen, Yiru, Yu, Dejie, Hiel, Hakim, Liao, Ping, Yue, David T., Fuchs, Paul A., Soong, Tuck Wah
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674741/
https://ncbi.nlm.nih.gov/pubmed/17050708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2093-06.2006
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