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Alternative Splicing at N Terminus and Domain I Modulates Ca(V)1.2 Inactivation and Surface Expression

The Ca(V)1.2 L-type calcium channel is a key conduit for Ca(2+) influx to initiate excitation-contraction coupling for contraction of the heart and vasoconstriction of the arteries and for altering membrane excitability in neurons. Its α(1C) pore-forming subunit is known to undergo extensive alterna...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Bartels, Peter, Yu, Dejie, Huang, Hua, Hu, Zhenyu, Herzig, Stefan, Soong, Tuck Wah
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961463/
https://ncbi.nlm.nih.gov/pubmed/29742403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.029
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